Author's response to reviews Title: Genomic Variation in Myeloma: Design, content, and initial application of the Bank On A Cure SNP Panel to detect associations with progression free survival Authors:

Genomic variation in myeloma: design, content, and initial application of the Bank On A Cure SNP Panel to detect associations with progression-free survival

BACKGROUND We have engaged in an international program designated the Bank On A Cure, which has established DNA banks from multiple cooperative and institutional clinical trials, and a platform for examining the association of genetic variations with disease risk and outcomes in multiple myeloma. We describe the development and content of a novel custom SNP panel that contains 3404 SNPs in 983 ...

Characteristics and outcomes of patients with multiple myeloma : Data from a developing country

Background: Multiple myeloma (MM) is a plasma cell disorder characterized by presence of monoclonal protein in serum or urine or both, increased bone marrow plasma cells, osteolytic lesion, hypercalcemia, and anemia. Several combination regimens are commonly recommended for treatment of multiple myeloma. The present study aimed at determining the characteristics and outcomes of patients with mu...

Author's response to reviews Title: Irradiation of the Potential Cancer Stem Cell Niches in the Adult Brain Improves Progression-free Survival of Patients with Malignant Glioma Authors:

A statement regarding the approval of the study by the local ethics board has been added.

Author's response to reviews Title: Effect Modification of Air pollution on Urinary 8-Hydroxy-2'-Deoxyguanosine by Genotypes -- an Application of the Multiple Testing Procedure to Identify Significant SNP Interactions Authors:

P-244: Analysis of Genomic and Cell Free DNA of A let-7 microRNA Binding Site of KRAS Gene Polymorphisms in Endometriosis

Background: Endometriosis is one of the most common benign gynecological diseases which is characterized by endometriallike tissue growing outside the uterine cavity. Although the pathology of endometriosis remains unknown, the genetic predisposition plays an apparent role. Several genes have been contributed to endometriosis, but it seems KRAS has a crucial role, because its activation results...